Bills vs. Vikings prediction, odds, spread, line: 2022 NFL picks, Week 10 best bets from proven comp

Publish date: 2024-08-16
USATSI

Teams with Super Bowl aspirations meet in Week 10 when the Minnesota Vikings (7-1) travel to Highmark Stadium to take on the Buffalo Bills (6-2). The Vikings are coming off a hard-fought 20-17 win over the Washington Commanders, while the Bills are hoping to bounce back from a 20-17 loss to the New York Jets. The Bills could be without MVP candidate Josh Allen, who injured his elbow on Buffalo's final offensive possession against the Jets. He's listed as a game-time decision for Sunday's showdown.

Kickoff is at 1 p.m. ET. Buffalo is favored by 6.5 points in the latest Bills vs. Vikings odds from Caesars Sportsbook, and the over/under is set at 46.5 points. Before making any Vikings vs. Bills picks, you need to see the NFL predictions and betting advice  from the proven simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 of the 2022 NFL season on an incredible 151-108 run on top-rated NFL picks that dates back to the 2017 season. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Bills vs. Vikings and just locked in its picks and NFL Week 10 predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting lines for Vikings vs. Bills:

What you need to know about the Bills

It was close but no cigar for the Bills as they fell 20-17 to the New York Jets this past Sunday. A silver lining for Buffalo was the play of QB Josh Allen, who accumulated 205 passing yards in addition to rushing for two TDs and 86 yards. Allen injured his elbow on Buffalo's final possession against the Jets, and is officially listed as a game-time decision for this week's game against Minnesota. 

Buffalo All-Pro wide receiver Stefon Diggs will be facing his former team for the first time since being traded to Buffalo before the 2020 season. For the season, Diggs has recorded 60 receptions for 857 yards and seven touchdowns. 

What you need to know about the Vikings

Minnesota continues to find ways to win close games -- a sign that they may legitimately be ready to contend in a wide open NFC race. This past Sunday Minnesota sidestepped the Washington Commanders for a 20-17 win. Wide receiver Justin Jefferson looked sharp as he caught seven passes for 115 yards and one TD. 

Like Diggs, Jefferson is having another dominant season for Minnesota. The third-year pro out of LSU ranks second in the NFL in receiving yards (867) and fifth in receptions (59). Running back Dalvin Cook has also been impressive under first-year head coach Kevin O'Connell, rushing for 608 yards and five touchdowns while catching 19 passes for 119 yards and a touchdown. 

How to make Vikings vs. Bills picks

The model has simulated Bills vs. Vikings 10,000 times and the results are in. The model is leaning Over on the point total, and it also says one side of the spread hits well over 50% of the time. You can only see the model's pick at SportsLine.

So who wins Vikings vs. Bills? And which side of the spread hits well over 50% of the time? Visit SportsLine right now to find out which side of the Bills vs. Vikings spread you should be all over, all from the model on a 151-108 roll on its top-rated NFL picks, and find out.

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